For the visually challenged, services are available in large print, Braille, audio formats, recorded books and talking books. The assistive technology employed includes the JAWS (Job Access with Speech) voice synthesizer, Magic Professional Screen Magnifier for those with low vision, the Braille Embosser, which translates text to Braille and printed material, and the Poet OCR reading machine for reading documents to the visually challenged. These services are available in Children's, Adult and Heritage libraries.

NALIS has also introduced the Visually Impaired Persons (VIP) Transport Service.  This service caters to visually impaired who need transport to access NALIS library. Transportation services are currently available to the National Library, Port of Spain, Carnegie Free Library, San Fernando, Arima Public Library, Maloney Public Library, Point Fortin Public Library and Princes Town Public Library.

NALIS provides easy access to persons in wheel chairs via ramps at street level and elevator access from the ground floor to the other service levels. Water fountains and bathroom facilities are designed for easy accessibility to wheel chair users.

Through the kind sponsorship of one of the Friends of the Library, a scooter is made available for persons not able to cover the large span of the library on foot. There are special workstations for the mobility impaired, equipped with special mouse devices and key pads.

NALIS’ staff has been trained in sign language to effectively communicate with the hearing impaired; staff can also communicate with the hearing impaired using the computer.